If you are right handed you should have more control holding the fish pole in your left hand and visa versa. I have more power pulling in a fish with my dominant arm.

I always hold a spinning rod in my right hand and used to hold a casting rod the same way but I tore a tendon just below my left elbow and couldn't hold the pole in that hand but I could still reel with it so at my next tourny I used a left hand casting reel and have never gone back.
It might take a trip or two to get used to it but I'm very comfortable with a left hand casting reel.

Now this, I usually use a right hand casting reel when fishing out of my salt boat so go figure. LOL.